Charles Lewis Wrenn (1880–1952) was an American illustrator and painter active in New York and later Connecticut.

He studied with William Merritt Chase and at the Art Students League. His early assignments included story illustrations for The Red Book Magazine, People’s Home Journal and The Housewife, along with covers for Breezy Stories. From the 1920s into the mid-1930s, Wrenn freelanced for pulp magazines such as Danger Trail, People’s Magazine, Ranch Romances, Three Star Magazine and War Stories, and supplied interior art to Clues. After traveling abroad to study art following World War I, he settled in South Norwalk, Connecticut, in 1936. He then concentrated on portraits and landscapes.